Update on recommendations on antiretroviral regimens for treating and preventing HIV infection: In 2016, WHO published the consolidated guidelines on the use of antiretroviral (ARV) drugs for treating and preventing HIV infection and recommended tenofovir disoproxil fumarate (TDF) + lamivudine (3TC) (or ...
WHO guidelines on HIV and Infant Feeding in 2010 for the first time recommended the use of antiretroviral drugs to prevent postnatal transmission of HIV through breastfeeding. This resulted in a major change from an individualised counselling approach toward a public health approach regarding how materna...
This early-release guideline makes available two key recommendations that were developed during the revision process in 2015. First, antiretroviral therapy (ART) should be initiated in everyone living with HIV at any CD4 cell count. Second, the use of daily oral pre-exposure prophylaxis (PrEP) is recomme...
Adolescents (10–19 years) and young people (20–24 years) continue to be vulnerable, both socially and economically, to HIV infection despite efforts to date. This is particularly true for adolescents — especially girls — who live in settings with a generalized HIV epidemic or who are members of k...
These recommendations have been developed specifically to address the daily use of antiretrovirals in HIV-uninfected people to block the acquisition of HIV infection. This prevention approach is known as pre-exposure prophylaxis. At this stage evidence is available from studies with two groups: men and t...
Over 1000 new cases of mother-to-child transmission of the human immunodeficiency virus (HIV) occur worldwide every day, making this the main route of transmission of HIV infection in children. Vitamin A deficiency affects about 19 million pregnant women, mostly from the WHO regions of Africa and South-E...
HIV-infected infants frequently present with clinical symptoms in the first year of life. Without effective treatment, an estimated one third of infected infants will have died by one year of age, and about half will have died by two years of age. These treatment guidelines serve as a framework for selec...
For the first time, the elimination of mother-to-child transmission of HIV (MTCT) is now considered a realistic public health goal and an important part of the campaign to achieve the millennium development goals. The 2010 revised PMTCT recommendations are based on two key approaches; lifelong ART for HI...
WHO guidelines for ART for HIV infection in adults and adolescents were originally published in 2002, and were revised in 2003 and 2006. New evidence has emerged on when to initiate ART, optimal ART regimens, the management of HIV coinfection with tuberculosis and chronic viral hepatitis, and the managem...
This publication summarizes current knowledge on the methods of diagnosing HIV infection in infants and children and sets out recommendations for practice and policy. Recommendations are designed to improve clinical management of the HIV-exposed and ‑infected child, and improve programme efforts at ear...